PUBLICATIONS 

Papers

Teresa M. Ribeiro-Rodrigues, Tiago L. Laundos, Rita Pereira-Carvalho, Daniela Batista-Almeida, Ricardo Pereira, Vanessa Coelho-Santos, Ana P. Silva, Rosa Fernandes, Monica Zuzarte, Francisco J. Enguita, Marina C. Costa, Perpetua Pinto-do-Ó, Marta T. Pinto, Pedro Gouveia, Lino Ferreira, Justin C. Mason, Paulo Pereira, Brenda R. Kwak, Diana S. Nascimento, Henrique Girão; Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis. Cardiovasc Res 2017 cvx118. doi: 10.1093/cvr/cvx118

Antunes JC, Pereira CL, Teixeira GQ, Silva RV, Caldeira J, Grad S, Gonçalves RM, Barbosa MA, Poly(-glutamic acid) and poly(-glutamic acid)-based nanocomplexes enhance type II collagen production in intervertebral disc, J Mater Sci Mater Med. 2017;28(1):6.

Almeida A, Silva D, Gonçalves V, Sarmento B. Synthesis and characterization of chitosan-grafted-polycaprolactone micelles for modulate intestinal paclitaxel delivery. Drug Deliv Transl Res. 2017 Jan 23.

Teixeira GQ, Leite Pereira C, Castro F, Ferreira JR, Gomez-Lazaro M, Aguiar P, Barbosa MA, Neidlinger-Wilke C, Goncalves RM, Anti-inflammatory Chitosan/Poly-glutamic acid nanoparticles control inflammation while remodeling extracellular matrix in degenerated intervertebral disc. Acta Biomater. 2016; 42:168-79

Cunha C, Almeida CR, Almeida MI, Silva AM, Molinos M, Lamas S, Pereira CL, Teixeira GQ, Monteiro A, Santos SG, Gonçalves RM, Barbosa MA. Systemic delivery of bone marrow MSCs for in situ intervertebral disc regeneration. Stem Cellls Translational Medicine. 2016. doi: 10.5966/sctm.2016-0033

Daniel M. Vasconcelos, Raquel M Gonçalves, Catarina R Almeida, Inês O Pereira, Marta I Oliveira, Nuno Neves, Andreia M Silva, António C Ribeiro, Carla Cunha, Ana R Almeida, Cristina C. Ribeiro, Ana M. Gil, Elisabeth Seebach, Katharyna L. Kynast, Wiltrud Richter, Meriem Lamghari, Susana G Santos and Mário A Barbosa. Fibrinogen scaffolds with immunomodulatory properties promote in vivo bone regeneration. Biomaterials 2016;111:163-178

I.C. Gonçalves, A. Magalhães, A.M.S. Costa, J.R. Oliveira, P.C. Henriques, P. Gomes, C.A. Reis, M.C.L. Martins. Bacteria-targeted biomaterials: glycan-coated microspheres to bind Helicobacter pylori. Acta Biomaterialia 2016; 33:40–50

Bidarra SJ, Oliveira P, Rocha S, Saraiva DP, Oliveira C, Barrias CC. A 3D in vitro model to explore the inter-conversion between epithelial and mesenchymal states during EMT and its reversion. Sci Rep. 2016 Jun 3;6:27072.

Salgado, C. L., Grenho, L., Fernandes, M. H., Colaco, B. J., & Monteiro, F. J. (2016). Biodegradation, biocompatibility, and osteoconduction evaluation of collagen-nanohydroxyapatite cryogels for bone tissue regeneration. J Biomed Mater Res A, 104(1), 57-70

Bento AR, Quelhas P, Oliveira MJ, Pêgo AP, Amaral IF. Three-dimensional culture of single embryonic stem-derived neural/stem progenitor cells in fibrin hydrogels: neuronal network formation and matrix remodelling. J Tissue Eng Regen Med. 2016 Dec 29.

Alves CJ, Alencastre IS, Neto E, Ribas J, Ferreira S, Vasconcelos DM, Sousa DM, Summavielle T, Lamghari M. Bone Injury and Repair Trigger Central and Peripheral NPY Neuronal Pathways. PLoS One. 2016 Nov 1;11(11):e0165465.

Lopes CD, Gomes CP, Neto E, Sampaio P, Aguiar P, Pêgo AP. Microfluidic-based platform to mimic the in vivo peripheral administration of neurotropic nanoparticles. Nanomedicine (Lond). 2016 Dec;11(24):3205-3221.

Barbosa JP, Neves AR, Silva AM, Barbosa MA, Reis MS, Santos SG. Nanostructured lipid carriers loaded with resveratrol modulate human dendritic cells. Int J Nanomedicine. 2016 Jul 28;11:3501-16. doi: 10.2147/IJN.S108694.

Ribeiro M, Ferraz MP, Monteiro FJ, Fernandes MH, Beppu MM, Mantione D, Sardon H. Antibacterial silk fibroin/nanohydroxyapatite hydrogels with silver and gold nanoparticles for bone regeneration. Nanomedicine. 2017 Jan;13(1):231-239.

Caires HR, Esteves T, Quelhas P, Barbosa MA, Navarro M, Almeida CR. Macrophage interactions with polylactic acid and chitosan scaffolds lead to improved recruitment of human mesenchymal stem/stromal cells: a comprehensive study with different immune cells. J R Soc Interface. 2016 Sep;13(122).

Sousa DM, Conceição F, Silva DI, Leitão L, Neto E, Alves CJ, Alencastre IS, Herzog H, Aguiar P, Lamghari M. Ablation of Y1 receptor impairs osteoclast bone-resorbing activity. Sci Rep. 2016 Sep 20;6:33470.

Silva AC, Rodrigues SC, Caldeira J, Nunes AM, Sampaio-Pinto V, Resende TP, Oliveira MJ, Barbosa MA, Thorsteinsdóttir S, Nascimento DS, Pinto-do-Ó P. Three-dimensional scaffolds of fetal decellularized hearts exhibit enhanced potential to support cardiac cells in comparison to the adult. Biomaterials. 2016 Oct;104:52-64.

Laranjeira MS, Moço A, Ferreira J, Coimbra S, Costa E, Santos-Silva A, Ferreira PJ, Monteiro FJ. Different hydroxyapatite magnetic nanoparticles for medical imaging: Its effects on hemostatic, hemolytic activity and cellular cytotoxicity. Colloids Surf B Biointerfaces. 2016 Oct 1;146:363-74.

Laundos TL, Silva J, Assunção M, Quelhas P, Monteiro C, Oliveira C, Oliveira MJ, Pêgo AP, Amaral IF. Rotary orbital suspension culture of embryonic stem cell-derived neural stem/progenitor cells: impact of hydrodynamic culture on aggregate yield, morphology and cell phenotype. J Tissue Eng Regen Med. 2016 Feb 15.

Costa-Rodrigues J, Carmo S, Perpétuo IP, Monteiro FJ, Fernandes MH. Osteoclastogenic differentiation of human precursor cells over micro- and nanostructured hydroxyapatite topography. Biochim Biophys Acta. 2016 Apr;1860(4):825-35.

Carvalho A, Pelaez-Vargas A, Hansford DJ, Fernandes MH, Monteiro FJ. Effects of Line and Pillar Array Microengineered SiO2 Thin Films on the Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells. Langmuir. 2016 Feb 2;32(4):1091-100.

Teresa Pinto A, Laranjeiro Pinto M, Patrícia Cardoso A, Monteiro C, Teixeira Pinto M, Filipe Maia A, Castro P, Figueira R, Monteiro A, Marques M, Mareel M, Dos Santos SG, Seruca R, Adolfo Barbosa M, Rocha S, José Oliveira M. Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities. Sci Rep. 2016 Jan 6;6:18765.

Moreno PM, Santos JC, Gomes CP, Varela-Moreira A, Costa A, Leiro V, Mansur H, Pêgo AP. Delivery of Splice Switching Oligonucleotides by Amphiphilic Chitosan-Based Nanoparticles. Mol Pharm. 2016 Feb 1;13(2):344-56.

Cardoso AP, Gonçalves RM, Antunes JC, Pinto ML, Pinto AT, Castro F, Monteiro C, Barbosa MA, Oliveira MJ. An interferon-γ-delivery system based on chitosan/poly(γ-glutamic acid) polyelectrolyte complexes modulates macrophage-derived stimulation of cancer cell invasion in vitro. Acta Biomater. 2015 Sep 1;23:157-71.

Silva AM, Varela-Moreira A, Pereira Gomes C, Molinos M, Leite M, Almeida M, Ribeiro D, Schrader M, Figueiredo C, Barbosa M, Gonçalves R, Almeida C, Pêgo A, Santos SG, Gomez-Lazaro M. Integrated Analysis of Biological Samples by Imaging Flow Cytometry. Microsc Microanal. 2015 Aug;21 Suppl 5:95-6.

Molinos M, Almeida CR, Gonçalves RM, Barbosa MA. Improvement of Bovine Nucleus Pulposus Cells Isolation Leads to Identification of Three Phenotypically Distinct Cell Subpopulations. Tissue Eng Part A. 2015 Aug;21(15-16):2216-27.

Lopes CD, Gomez-Lazaro M, Pêgo AP. Seeing is believing but quantifying is deciding. Nanomedicine (Lond). 2015 Aug;10(15):2307-10.

Salgado CL, Grenho L, Fernandes MH, Colaço BJ, Monteiro FJ. Biodegradation, biocompatibility, and osteoconduction evaluation of collagen-nanohydroxyapatite cryogels for bone tissue regeneration. J Biomed Mater Res A. 2015 Jul 14.

Cardoso AP, Pinto ML, Pinto AT, Pinto MT, Monteiro C, Oliveira MI, Santos SG, Relvas JB, Seruca R, Mantovani A, Mareel M, Barbosa MA, Oliveira MJ. Matrix metalloproteases as maestros for the dual role of LPS- and IL-10-stimulated macrophages in cancer cell behaviour. BMC Cancer. 2015 Jun 5;15:456.

Barros J, Grenho L, Fernandes MH, Manuel CM, Melo LF, Nunes OC, Monteiro FJ, Ferraz MP. Anti-sessile bacterial and cytocompatibility properties of CHX-loaded nanohydroxyapatite. Colloids Surf B Biointerfaces. 2015 Jun 1;130:305-14.

Caires HR, Gomez-Lazaro M, Oliveira CM, Gomes D, Mateus DD, Oliveira C, Barrias CC, Barbosa MA, Almeida CR. Finding and tracing human MSC in 3D microenvironments with the photoconvertible protein Dendra2. Sci Rep. 2015 May 14;5:10079.

Barros J, Grenho L, Fernandes MH, Manuel CM, Melo LF, Nunes OC, Monteiro FJ, Ferraz MP. Anti-sessile bacterial and cytocompatibility properties of CHX-loaded nanohydroxyapatite. Colloids Surf B Biointerfaces. 2015 Apr 21. pii:S0927-7765(15)00252-0.

Pereira C, Araújo F, Barrias CC, Granja PL, Sarmento B. Dissecting stromal-epithelial interactions in a 3D in vitro cellularized intestinal model for permeability studies. Biomaterials. 2015 Jul;56:36-45.

das Neves J, Sarmento B. Precise engineering of dapivirine-loaded nanoparticles for the development of anti-HIV vaginal microbicides. Acta Biomater. 2015 May;18:77-87.

Coelho CC, Sousa SR, Monteiro FJ. Heparinized nanohydroxyapatite/collagen granules for controlled release of vancomycin. J Biomed Mater Res A. 2015 Mar 16.

Grenho L, Barros J, Ferreira C, Santos VR, Monteiro FJ, Ferraz MP, Cortes ME. In vitro antimicrobial activity and biocompatibility of propolis containing nanohydroxyapatite. Biomed Mater. 2015 Mar 18;10(2):025004

Andrade F, Fonte P, Oliva M, Videira M, Ferreira D, Sarmento B. Solid state formulations composed by amphiphilic polymers for delivery of proteins: characterization and stability. Int J Pharm. 2015 May 30;486(1-2):195-206.

de Oliveira JT, Santos AL, Gomes C, Barros R, Ribeiro C, Mendes N, de Matos AJ, Vasconcelos MH, Oliveira MJ, Reis CA, Gärtner F. Anti-influenza neuraminidase inhibitor oseltamivir phosphate induces canine mammary cancer cell aggressiveness. PLoS One. 2015 Apr 7;10(4):e0121590.

Kapoor S, Semitela Â, Goel A, Xiang Y, Du J, Lourenço AH, Sousa DM, Granja PL, Ferreira JM. Understanding the composition-structure-bioactivity relationships in diopside (CaO·MgO·2SiO₂)-tricalcium phosphate (3CaO·P₂O₅) glass system. Acta Biomater. 2015 Mar;15:210-26.

das Neves J, Nunes R, Machado A, Sarmento B. Polymer-based nanocarriers for vaginal drug delivery. Adv Drug Deliv Rev. 2014 Dec 27. 

Pires LR, Rocha DN, Ambrosio L, Pêgo AP. The role of the surface on microglia function: implications for central nervous system tissue engineering. J R Soc Interface. 2015 Feb 6;12(103). pii: 20141224.

Nunes JB, Peixoto J, Soares P, Maximo V, Carvalho S, Pinho SS, Vieira AF, Paredes J, Rego AC, Ferreira IL, Gomez-Lazaro M, Sobrinho-Simoes M, Singh KK, Lima J. OXPHOS dysfunction regulates integrin-β1 modifications and enhances cell motility and migration. Hum Mol Genet. 2015 Apr 1;24(7):1977-90.

Vasconcelos DP, Costa M, Amaral IF, Barbosa MA, Águas AP, Barbosa JN. Modulation of the inflammatory response to chitosan through M2 macrophage polarization using pro-resolution mediators. Biomaterials. 2015 Jan;37:116-23.

Parreira P, Shi Q, Magalhaes A, Reis CA, Bugaytsova J, Borén T, Leckband D, Martins MC. Atomic force microscopy measurements reveal multiple bonds between Helicobacter pylori blood group antigen binding adhesin and Lewis b ligand. J R Soc Interface. 2014 Dec 6;11(101):20141040. 

Nunes R, Sarmento B, das Neves J. Formulation and delivery of anti-HIV rectal microbicides: advances and challenges. J Control Release. 2014 Nov 28;194:278-94.

Pagella P, Neto E, Jiménez-Rojo L, Lamghari M, Mitsiadis TA. Microfluidics co-culture systems for studying tooth innervation. Front Physiol. 2014 Aug 25;5:326.

Valente M, Nascimento DS, Cumano A, Pinto-do-Ó P. Sca-1+ cardiac progenitor cells and heart-making: a critical synopsis. Stem Cells Dev. 2014 Oct 1;23(19):2263-73.

Maia FR, Barbosa M, Gomes DB, Vale N, Gomes P, Granja PL, Barrias CC. Hydrogel depots for local co-delivery of osteoinductive peptides and mesenchymal stem cells. J Control Release. 2014 Sep 10;189:158-68.

Ribeiro N, Sousa SR, van Blitterswijk CA, Moroni L, Monteiro FJ. A biocomposite of collagen nanofibers and nanohydroxyapatite for bone regeneration. Biofabrication. 2014 Sep;6(3):035015.

Bordeira-Carriço R, Ferreira D, Mateus DD, Pinheiro H, Pêgo AP, Santos MA, Oliveira C. Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA. Eur J Hum Genet. 2014 Sep;22(9):1085-92.

Costa F, Maia S, Gomes J, Gomes P, Martins MC. Characterization of hLF1-11 immobilization onto chitosan ultrathin films, and its effects on antimicrobial activity. Acta Biomater. 2014 Aug;10(8):3513-21.

Maia FR, Fonseca KB, Rodrigues G, Granja PL, Barrias CC. Matrix-driven formation of mesenchymal stem cell-extracellular matrix microtissues on soft alginate hydrogels. Acta Biomater. 2014 Jul;10(7):3197-208.

Maia FR, Lourenço AH, Granja PL, Gonçalves RM, Barrias CC. Effect of cell density on mesenchymal stem cells aggregation in RGD-alginate 3D matrices under osteoinductive conditions. Macromol Biosci. 2014 Jun;14(6):759-71.

Freire AG, Nascimento DS, Forte G, Valente M, Resende TP, Pagliari S, Abreu C, Carvalho I, Di Nardo P, Pinto-do-Ó P. Stable phenotype and function of immortalized Lin-Sca-1+ cardiac progenitor cells in long-term culture: a step closer to standardization. Stem Cells Dev. 2014 May 1;23(9):1012-26.

Lima L, Oliveira D, Tavares A, Amaro T, Cruz R, Oliveira MJ, Ferreira JA, Santos L. The predominance of M2-polarized macrophages in the stroma of low-hypoxic bladder tumors is associated with BCG immunotherapy failure. Urol Oncol. 2014 May;32(4):449-57.

Bidarra SJ, Barrias CC, Granja PL. Injectable alginate hydrogels for cell delivery in tissue engineering. Acta Biomater. 2014 Apr;10(4):1646-62.

Guerreiro SG, Oliveira MJ, Barbosa MA, Soares R, Granja PL. Neonatal human dermal fibroblasts immobilized in RGD-alginate induce angiogenesis. Cell Transplant. 2014;23(8):945-57.

Silva AM, Oliveira MI, Sette L, Almeida CR, Oliveira MJ, Barbosa MA, Santos SG. Resveratrol as a natural anti-tumor necrosis factor-α molecule: implications to dendritic cells and their crosstalk with mesenchymal stromal cells. PLoS One. 2014 Mar 10;9(3):e91406.

Rocha DN, Brites P, Fonseca C, Pêgo AP. Poly(trimethylene carbonate-co-ε-caprolactone) promotes axonal growth. PLoS One. 2014 Feb 27;9(2):e88593.

Maciel J, Oliveira MI, Colton E, McNally AK, Oliveira C, Anderson JM, Barbosa MA. Adsorbed fibrinogen enhances production of bone- and angiogenic-related factors by monocytes/macrophages. Tissue Eng Part A. 2014 Jan;20(1-2):250-63.

Gonçalves IC, Magalhães A, Fernandes M, Rodrigues IV, Reis CA, Martins MC. Bacterial-binding chitosan microspheres for gastric infection treatment and prevention. Acta Biomater. 2013 Dec;9(12):9370-8.

Vasconcelos DP, Fonseca AC, Costa M, Amaral IF, Barbosa MA, Águas AP, Barbosa JN. Macrophage polarization following chitosan implantation. Biomaterials. 2013 Dec;34(38):9952-9.

Maia FR, Bidarra SJ, Granja PL, Barrias CC. Functionalization of biomaterials with small osteoinductive moieties. Acta Biomater. 2013 Nov;9(11):8773-89.

Parreira P, Magalhães A, Reis CA, Borén T, Leckband D, Martins MC.Bioengineered surfaces promote specific protein-glycan mediated binding of the gastric pathogen Helicobacter pylori. Acta Biomater. 2013 Nov;9(11):8885-93.

Fernandes M, Gonçalves IC, Nardecchia S, Amaral IF, Barbosa MA, Martins MC. Modulation of stability and mucoadhesive properties of chitosan microspheres for therapeutic gastric application. Int J Pharm. 2013 Sep 15;454(1):116-24.

Barros J, Grenho L, Manuel CM, Ferreira C, Melo LF, Nunes OC, Monteiro FJ, Ferraz MP. A modular reactor to simulate biofilm development in orthopedic materials. Int Microbiol. 2013 Sep;16(3):191-8.

Laranjeira MS, Fernandes MH, Monteiro FJ. Response of monocultured and co-cultured human microvascular endothelial cells and mesenchymal stem cells to macroporous granules of nanostructured-hydroxyapatite agglomerates. J Biomed Nanotechnol. 2013 Sep;9(9):1594-606.

Pires LR, Guarino V, Oliveira MJ, Ribeiro CC, Barbosa MA, Ambrosio L, Pêgo AP. Ibuprofen-loaded poly(trimethylene carbonate-co-ε-caprolactone) electrospun fibres for nerve regeneration. J Tissue Eng Regen Med. 2013 Aug 16.

Santos SG, Lamghari M, Almeida CR, Oliveira MI, Neves N, Ribeiro AC, Barbosa JN, Barros R, Maciel J, Martins MC, Gonçalves RM, Barbosa MA. Adsorbed fibrinogen leads to improved bone regeneration and correlates with differences in the systemic immune response. Acta Biomater. 2013 Jul;9(7):7209-17.

Pelaez-Vargas A, Gallego-Perez D, Carvalho A, Fernandes MH, Hansford DJ, Monteiro FJ. Effects of density of anisotropic microstamped silica thin films on guided bone tissue regeneration--in vitro study. J Biomed Mater Res B Appl Biomater. 2013 Jul;101(5):762-9.

Torres AL, Santos SG, Oliveira MI, Barbosa MA. Fibrinogen promotes resorption of chitosan by human osteoclasts. Acta Biomater. 2013 May;9(5):6553-62.

Amaral IF, Sousa SR, Neiva I, Marcus-Silva L, Kirkpatrick CJ, Barbosa MA, Pêgo AP. Kinetics and isotherm of fibronectin adsorption to three-dimensional porous chitosan scaffolds explored by ( 125) I-radiolabelling. Biomatter. 2013 Apr 29;3(3).

Torres AL, Santos SG, Oliveira MI, Barbosa MA. Fibrinogen promotes resorption of chitosan by human osteoclasts. Acta Biomater. 2013
Tags: Fluorescence microscopy

Pelaez-Vargas A, Gallego-Perez D, Carvalho A, Fernandes MH, Hansford DJ, Monteiro FJ. Effects of density of anisotropic microstamped silica thin films on guided bone tissue regeneration—In vitro study. J Biomed Mater Res B Appl Biomater. 2013
Tags: Fluorescence microscopy, image analysis

Pinto AM, Moreira S, Gonçalves IC, Gama FM, Mendes AM, Magalhães FD. Biocompatibility of poly(lactic acid) with incorporated graphene-based materials. Colloids Surf B Biointerfaces. 2012
Tags: Fluorescence microscopy

Martins S, Tho I, Reimold I, Fricker G, Souto E, Ferreira D, Brandl M. Brain delivery of camptothecin by means of solid lipid nanoparticles: Formulation design, in vitro and in vivo studies. Int J Pharm. 2012
Tags: Confocal microscopy

Rodrigues SC, Salgado CL, Sahu A, Garcia MP, Fernandes MH, Monteiro FJ. Preparation and characterization of collagen-nanohydroxyapatite biocomposite scaffolds by cryogelation method for bone tissue engineering applications. J Biomed Mater Res A. 2012
Tags: Confocal microscopy

Carvalho A, Pelaez-Vargas A, Gallego-Perez D, Grenho L, Fernandes MH, De Aza AH, Ferraz MP, Hansford DJ, Monteiro FJ. Micropatterned silica thin films with nanohydroxyapatite micro-aggregates for guided tissue regeneration. Dent Mater. 2012
Tags: AFM, Fluorescence microscopy

Maciel J, Oliveira MI, Gonçalves RM, Barbosa MA. The effect of adsorbed fibronectin and osteopontin on macrophage adhesion and morphology on hydrophilic and hydrophobic model surfaces. Acta Biomater. 2012
Tags: Confocal microscopy

Laranjeira MS, Fernandes MH, Monteiro FJ. Reciprocal induction of human dermal microvascular endothelial cells and human mesenchymal stem cells: time-dependent profile in a co-culture system. Cell Prolif 2012
Tags: Confocal microscopy

Ribeiro AR, Barbaglio A, Oliveira MJ, Santos R, Coelho AV, Ribeiro CC, Wilkie IC, Carnevali MD, Barbosa MA. Correlations between the biochemistry and mechanical states of a sea-urchin ligament: a mutable collagenous structure. Biointerphases. 2012
Tags: Confocal Raman

Almeida CR, Vasconcelos DP, Gonçalves RM, Barbosa MA. Enhanced mesenchymal stromal cell recruitment via natural killer cells by incorporation of inflammatory signals in biomaterials. J R Soc Interface . 2012
Tags: Confocal microscopy, fluorescence  microscopy

Antunes JC, Pereira CL, Molinos M, Ferreira-da-Silva F, Dessì M, Gloria A, Ambrosio L, Gonçalves RM, Barbosa MA. Layer-by-layer self-assembly of chitosan and poly(γ-glutamic acid) into polyelectrolyte complexes. Biomacromolecules. 2011
Tags: AFM

Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Amédée J, Granja PL. Phenotypic and proliferative modulation of human mesenchymal stem cells via crosstalk with endothelial cells. Stem Cell Res . 2011
Tags: Fluorescence microscopy

Bidarra SJ, Barrias CC, Fonseca KB, Barbosa MA, Soares RA, Granja PL. Injectable in situ crosslinkable RGD-modified alginate matrix for endothelial cells delivery. Biomaterials. 2011
Tags: Confocal microscopy

Pelaez-Vargas A, Gallego-Perez D, Magallanes-Perdomo M, Fernandes MH, Hansford DJ, De Aza AH, Pena P, Monteiro FJ. Isotropic micropatterned silica coatings on zirconia induce guided cell growth for dental implants. Dent Mater . 2011
Tags: Fluorescence microscopy, Confocal Raman

Oliveira H, Rangl M, Ebner A, Mayer B, Hinterdorfer P, Pêgo AP. Molecular recognition force spectroscopy: a new tool to tailor targeted nanoparticles. Small . 2011
Tags: AFM

Rocha R, Campilho A, Silva J, Azevedo E, Santos R. Segmentation of ultrasound images of the carotid using RANSAC and cubic splines. Comput Methods Programs Biome. 2011
Tags: Ultrasounds

Fonseca KB, Bidarra SJ, Oliveira MJ, Granja PL, Barrias CC. Molecularly designed alginate hydrogels susceptible to local proteolysis as three-dimensional cellular microenvironments. Acta Biomater. 2011
Tags: Confocal microscopy

Laranjeira MS, Fernandes MH, Monteiro FJ. Innovative macroporous granules of nanostructured-hydroxyapatite agglomerates: bioactivity and osteoblast-like cell behaviour. J Biomed Mater Res A. 2010
Tags: Confocal microscopy

Pelaez-Vargas A, Gallego-Perez D, Ferrell N, Fernandes MH, Hansford D, Monteiro FJ. Early spreading and propagation of human bone marrow stem cells on isotropic and anisotropic topographies of silica thin films produced via microstamping. Microsc Microanal. 2010
Tags: AFM, Fluorescence microscopy

Ribeiro N, Sousa SR, Monteiro FJ. Influence of crystallite size of nanophased hydroxyapatite on fibronectin and osteonectin adsorption and on MC3T3-E1 osteoblast adhesion and morphology. J Colloid Interface Sci. 2010
Tags: AFM, Fluorescence microscopy

Oliveira H, Pires LR, Fernandez R, Martins MC, Simões S, Pêgo AP. Chitosan-based gene delivery vectors targeted to the peripheral nervous system. J Biomed Mater Res A. 2010
Tags: Fluorescence Microscopy

Bidarra SJ, Barrias CC, Barbosa MA, Soares R, Granja PL. Immobilization of human mesenchymal stem cells within RGD-grafted alginate microspheres and assessment of their angiogenic potential. Biomacromolecules. 2010
Tags: Confocal microscopy

Gonçalves R, Martins MC, Oliveira MJ, Almeida-Porada G, Barbosa MA. Bioactivity of immobilized EGF on self-assembled monolayers: optimization of the immobilization process. J Biomed Mater Res A. 2010
Tags: Confocal microscopy

Oliveira H, Fernandez R, Pires LR, Martins MC, Simões S, Barbosa MA, Pêgo AP. Targeted gene delivery into peripheral sensorial neurons mediated by self-assembled vectors composed of poly(ethylene imine) and tetanus toxin fragment c. J Control Release. 2010
Tags: Fluorescence microscopy

Amaral IF, Unger RE, Fuchs S, Mendonça AM, Sousa SR, Barbosa MA, Pêgo AP, Kirkpatrick CJ. Fibronectin-mediated endothelialisation of chitosan porous matrices. Biomaterials. 2009
Tags: Confocal microscopy

Barrias CC, Martins MC, Almeida-Porada G, Barbosa MA, Granja PL. The correlation between the adsorption of adhesive proteins and cell behaviour on hydroxyl-methyl mixed self-assembled monolayers. Biomaterials. 2009
Tags: Confocal microscopy

Martins MC, Curtin SA, Freitas SC, Salgueiro P, Ratner BD, Barbosa MA. Molecularly designed surfaces for blood deheparinization using an immobilized heparin-binding peptide. J Biomed Mater Res A. 2009
Tags: AFM

Oliveira GM, Ferraz MP, González PG, Serra J, Leon B, Pèrez-Amor M, Monteiro FJ. PLD bioactive ceramic films: the influence of CaO-P2O5 glass additions to hydroxyapatite on the proliferation and morphology of osteblastic like-cells. J Mater Sci Mater Med. 2008
Tags: AFM

Mateus AY, Barrias CC, Ribeiro C, Ferraz MP, Monteiro FJ. Comparative study of nanohydroxyapatite microspheres for medical applications. J Biomed Mater Res A. 2008
Tags: Confocal microscopy

Teixeira S, Ferraz MP, Monteiro FJ. Biocompatibility of highly macroporous ceramic scaffolds: cell adhesion and morphology studies. J Mater Sci Mater Med. 2008
Tags: Confocal microscopy

Sousa SR, Lamghari M, Sampaio P, Moradas-Ferreira P, Barbosa MA. Osteoblast adhesion and morphology on TiO2 depends on the competitive preadsorption of albumin and fibronectin. J Biomed Mater Res A. 2008
Tags: Confocal microscopy

Amaral IF, Cordeiro AL, Sampaio P, Barbosa MA. Attachment, spreading and short-term proliferation of human osteoblastic cells cultured on chitosan films with different degrees of acetylation. J Biomater Sci Polym Ed. 2007
Tags: AFM

Evangelista MB, Hsiong SX, Fernandes R, Sampaio P, Kong HJ, Barrias CC, Salema R, Barbosa MA, Mooney DJ, Granja PL. Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix. Biomaterials. 2007
Tags: Confocal microscopy

Teixeira S, Monteiro FJ, Ferraz MP, Vilar R, Eugénio S. Laser surface treatment of hydroxyapatite for enhanced tissue integration: surface characterization and osteoblastic interaction studies. J Biomed Mater Res A. 2007
Tags: AFM, confocal microscopy.

Sousa SR, Brás MM, Moradas-Ferreira P, Barbosa MA. Dynamics of fibronectin adsorption on TiO2 surfaces. Langmuir. 2007
Tags: AFM

Botelho CM, Brooks RA, Best SM, Lopes MA, Santos JD, Rushton N, Bonfield W. Human osteoblast response to silicon-substituted hydroxyapatite. J Biomed Mater Res A. 2006
Tags: Confocal microscopy

Botelho CM, Brooks RA, Spence G, McFarlane I, Lopes MA, Best SM, Santos JD, Rushton N, Bonfield W. Differentiation of mononuclear precursors into osteoclasts on the surface of Si-substituted hydroxyapatite. J Biomed Mater Res A. 2006
Tags: Fluorescence microscopy

Amaral IF, Sampaio P, Barbosa MA. Three-dimensional culture of human osteoblastic cells in chitosan sponges: the effect of the degree of acetylation. J Biomed Mater Res A. 2006
Tags: Confocal microscopy, Fluorescense microscopy

Amaral IF, Lamghari M, Sousa SR, Sampaio P, Barbosa MA. Rat bone marrow stromal cell osteogenic differentiation and fibronectin adsorption on chitosan membranes: the effect of the degree of acetylation. J Biomed Mater Res A. 2005
Tags: AFM, Fluorescence microscopy, 

Barrias CC, Ribeiro CC, Lamghari M, Miranda CS, Barbosa MA. Proliferation, activity, and osteogenic differentiation of bone marrow stromal cells cultured on calcium titanium phosphate microspheres. J Biomed Mater Res A. 2005
Tags: Confocal microscopy, calcium titanium phosphate, microspheres, bone marrow stromal cells, osteogenic differentiation

Sousa SR, Moradas-Ferreira P, Saramago B, Melo LV, Barbosa MA. Human serum albumin adsorption on TiO2 from single protein solutions and from plasma. Langmuir. 2004
Tags: AFM, titanium

Leitão E, Barbosa MA, de Groot K.Influence of substrate material and surface finishing on the morphology of the calcium-phosphate coating. J Biomed Mater Res. 1997
Tags: AFM

Bravo I, Carvalho GS. Stimulation of human T lymphocytes via CD2 and CD3 molecules: establishment of the method and characterisation of proliferating cells. Cytobios. 1993
Tags: immunocytochemistry, metallic biomaterials, T lymphocyte

 

Conference Proceedings/Books of Abstract

A. Kuruvilla, P. Hennings Yeomans, P. Quelhas, J. Li, N. Shaikh, A. Hoberman, and J. Kovačević, Otitis media vocabulary and grammar. Proc. IEEE Int. Conf. Image Proc., Orlando, FL, Sep. 2012.

Duarte, C., Oliveira, H.P., Magalhaes, F., Tavares, V.G., Campilho, A.C., De Oliveira, P.G. Proactive engineering. IEEE global engineering education conference, EDUCON; 2012.

Esteves, T., Valente, M., Nascimento, D.S., Pinto-Do-Ó, P., Quelhas, P. Automatic myocardial infarction size extraction in an experimental murine model using an anatomical model. Proceedings - International Symposium on Biomedical Imaging, art. no. 6235546, pp. 310-313.

Gil-Jiménez P, Losilla-López B, Torres-Cueco R, Campilho A, López-Sastre R. Hand detection and tracking using the skeleton of the blob for medical rehabilitation applications. Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2012;7325 LNCS(PART 2):130-7.

Leal P, Ferro L, Marques M, Romão S, Cruz T, Tomá AM, Castro H, Quelhas P. Automatic assessment of leishmania infection indexes on in vitro macrophage cell cultures. Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2012;7325 LNCS(PART 2):432-9.

Mendonça AM, Cardoso F, Sousa AV, Campilho A. Automatic localization of the optic disc in retinal images based on the entropy of vascular directions. Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2012;7325 LNCS(PART 2):424-31.

Moreira BM, Sousa AV, Mendonça AM, Campilho A. Automatic lane detection in chromatography images.Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2012;7325 LNCS(PART 2):180-7.

Nascimento D, Silva A, Oliveira MJ, Barbosa MA, Pinto-do-Ó P. Dissection and reconstruction of the extracellular matrix - a cardiac regenerative niche (2012). (15.P24) Journal of Tissue Engineering and regenerative Medicine. 6 (Issue Supplement s1 - Special Issue: 3rd TERMIS World Congress 2012, 5-8 September 2012, Vienna, Austria): p. 110. In proceeding of: 3rd TERMIS World Congress 2012, At Vienna, Austria, Volume: Journal of Tissue Engineering and regenerative Medicine. 6 (Suppl.1): 1–429.

Ramos J, Kockelkorn T, Van Ginneken B, Viergever MA, Ramos R, Campilho A. Supervised content based image retrieval using radiology reports. Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2012;7325 LNCS(PART 2):249-58.

Rodrigues LR, Dias CGBT, Ceragioli HJ, Rodas ACD, Monteiro FJM, Zavaglia CAC. FTIR analysis and cytotoxicity test of titanium dioxide nanoparticles. Key Engineering Materials 2012;493-494:768-74.